CASE STUDY OF USING THE DOMESTIC ANALOGUE OF CYCLOSPORINE A

The article illustrates results of an important trial for the Russian pharmaceutical industry, an assessment of the efficacy and safety of domestic immunosuppressive medication Cyclosporine A. A comparative analysis was made of pharmacokinetics, hepato-, myelo- and renal toxicity of domestic Cyclosp...

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Main Authors: V.A. Goryainov (Author), M.M. Kaabak (Author), N.N. Babenko (Author), N.T. Vorob'eva (Author), L.A. Shishlo (Author), M.M. Morozova (Author), T.Yu. Cheprasova (Author)
Format: Book
Published: Union of pediatricians of Russia, 2010-09-01T00:00:00Z.
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Summary:The article illustrates results of an important trial for the Russian pharmaceutical industry, an assessment of the efficacy and safety of domestic immunosuppressive medication Cyclosporine A. A comparative analysis was made of pharmacokinetics, hepato-, myelo- and renal toxicity of domestic Cyclosporine A and Novartis-manufactured Cyclosporine A in patients with a renal allotransplant. The authors convincingly demonstrated the comparability by practically all studied parameters after a 2-week administration of the domestic analogue. Key words: Cyclosporine A, efficacy, safety, immunosuppression, kidney transplantation. (Pediatric Pharmacology. - 2010; 7(5):82-87)
Item Description:1727-5776
2500-3089