Successful treatment of platinum refractory ovarian clear cell carcinoma with secondary cytoreductive surgery and implantable transponder placement to facilitate targeted volumetric arc radiation therapy

We describe a case of the first successful treatment of platinum refractory clear cell ovarian cancer with secondary cytoreductive surgery and placement of Calypso transponders to facilitate post-operative volumetric arc radiation therapy. In the setting of both primary and recurrent disease, patien...

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Main Authors: Julia Fehniger (Author), Peter B. Schiff (Author), Bhavana Pothuri (Author)
Format: Book
Published: Elsevier, 2019-02-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Julia Fehniger  |e author 
700 1 0 |a Peter B. Schiff  |e author 
700 1 0 |a Bhavana Pothuri  |e author 
245 0 0 |a Successful treatment of platinum refractory ovarian clear cell carcinoma with secondary cytoreductive surgery and implantable transponder placement to facilitate targeted volumetric arc radiation therapy 
260 |b Elsevier,   |c 2019-02-01T00:00:00Z. 
500 |a 2352-5789 
500 |a 10.1016/j.gore.2018.11.004 
520 |a We describe a case of the first successful treatment of platinum refractory clear cell ovarian cancer with secondary cytoreductive surgery and placement of Calypso transponders to facilitate post-operative volumetric arc radiation therapy. In the setting of both primary and recurrent disease, patients with clear cell ovarian cancer are less responsive to standard chemotherapy and those treated with radiation therapy may have improved outcomes compared to the use of other treatment modalities. Volumetric arc radiation therapy with implantable transponders is feasible, and allows for the targeted treatment of sites of metastatic disease while limiting toxicity to surrounding structures and can be considered for patients with recurrent ovarian cancer and oligometastatic disease. Keywords: Clear cell carcinoma, Ovarian carcinoma, Pelvic radiation, Volumetric arc therapy 
546 |a EN 
690 |a Gynecology and obstetrics 
690 |a RG1-991 
690 |a Neoplasms. Tumors. Oncology. Including cancer and carcinogens 
690 |a RC254-282 
655 7 |a article  |2 local 
786 0 |n Gynecologic Oncology Reports, Vol 27, Iss , Pp 11-14 (2019) 
787 0 |n http://www.sciencedirect.com/science/article/pii/S2352578918301073 
787 0 |n https://doaj.org/toc/2352-5789 
856 4 1 |u https://doaj.org/article/c1a61757bf5a49b3be1e8739e63cb645  |z Connect to this object online.