Design, synthesis and biological activity of pyrazinamide derivatives for anti-Mycobacterium tuberculosis
A total of 11 pyrazinamide derivatives were designed and synthesised using pyrazinamide as the lead compound, which was optimised by structural modification with alkyl chains, six-membered rings, and bioisosterism, respectively. The target compounds were synthesised using pyrazinecarboxylic acid as...
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| Principais autores: | , , |
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| Formato: | Livro |
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Taylor & Francis Group,
2017-01-01T00:00:00Z.
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