The Coumarin-Derivative Esculetin Protects against Lipotoxicity in Primary Rat Hepatocytes via Attenuating JNK-Mediated Oxidative Stress and Attenuates Free Fatty Acid-Induced Lipid Accumulation

• Prif Awduron: Mengmeng Xia (Awdur), Zongmei Wu (Awdur), Junyu Wang (Awdur), Manon Buist-Homan (Awdur), Han Moshage (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: MDPI AG, 2023-10-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Coumarin derivates have been proposed as a potential treatment for metabolic-dysfunction-associated fatty liver disease (MAFLD). However, the mechanisms underlying their beneficial effects remain unclear. In the present study, we explored the potential of the coumarin derivate esculetin in MAFLD, fo...