Design, synthesis, and biological evaluation of novel iso-flavones derivatives as H3R antagonists

• প্রধান লেখক: Jian Xin (লেখক), Min Hu (লেখক), Qian Liu (লেখক), Tian Tai Zhang (লেখক), Dong Mei Wang (লেখক), Song Wu (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Histamine H3 receptor (H3R), a kind of G-protein coupled receptor (GPCR), is expressed mainly in the central nervous system (CNS) and plays a vital role in homoeostatic control. This study describes the design and synthesis of a series of novel H3R antagonists based on the iso-flavone scaffold. The...