Design, synthesis, and biological evaluation of novel iso-flavones derivatives as H3R antagonists
Histamine H3 receptor (H3R), a kind of G-protein coupled receptor (GPCR), is expressed mainly in the central nervous system (CNS) and plays a vital role in homoeostatic control. This study describes the design and synthesis of a series of novel H3R antagonists based on the iso-flavone scaffold. The...
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Taylor & Francis Group,
2018-01-01T00:00:00Z.
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A1234.567 |
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