Design, synthesis, and biological evaluation of novel iso-flavones derivatives as H3R antagonists

Histamine H3 receptor (H3R), a kind of G-protein coupled receptor (GPCR), is expressed mainly in the central nervous system (CNS) and plays a vital role in homoeostatic control. This study describes the design and synthesis of a series of novel H3R antagonists based on the iso-flavone scaffold. The...

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Principais autores: Jian Xin (Autor), Min Hu (Autor), Qian Liu (Autor), Tian Tai Zhang (Autor), Dong Mei Wang (Autor), Song Wu (Autor)
Formato: Livro
Publicado em: Taylor & Francis Group, 2018-01-01T00:00:00Z.
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