Progressive Thoracolumbar Tuberculosis in a Young Male: Diagnostic, Therapeutic, and Surgical Insights

• Main Authors: Dana-Georgiana Nedelea (Author), Diana Elena Vulpe (Author), George Viscopoleanu (Author), Alexandru Constantin Radulescu (Author), Alexandra Ana Mihailescu (Author), Sebastian Gradinaru (Author), Mihnea Orghidan (Author), Cristian Scheau (Author), Romica Cergan (Author), Serban Dragosloveanu (Author)
• Format: Book
• Published: MDPI AG, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 10.3390/idr16050080; 2036-7449
• Keywords: spinal tuberculosis; tuberculous spondylitis; surgical management; medical imaging; expandable cage reconstruction; multidisciplinary approach; Other systems of medicine; RZ201-999
• Source: Infectious Disease Reports, Vol 16, Iss 5, Pp 1005-1016 (2024)

Objective: We present the case of a 26-year-old male with severe spinal tuberculosis of the thoracolumbar region. The patient suffered from worsening back pain over five years, initially responding to over-the-counter analgesics. Despite being proposed surgery in 2019, the patient refused the intervention and subsequently experienced significant disease progression. Methods: Upon re-presentation in 2022, mild involvement of the T12-L1 vertebrae was recorded by imaging, leading to a percutaneous needle biopsy which confirmed tuberculosis. Despite undergoing anti-tuberculous therapy for one year, the follow-up in 2024 revealed extensive infection from T10 to S1, with large psoas abscesses and a pseudo-tumoral mass of the right thigh. The patient was ultimately submitted to a two-stage surgical intervention: anterior resection and reconstruction of T11-L1 with an expandable cage, followed by posterior stabilization from T8-S1. Results: Postoperative recovery was uneventful, with significant pain relief and no neurological deficits. The patient was discharged on a continued anti-tuberculous regimen and remains under close surveillance. Conclusions: This paper presents details on the challenges of diagnosis and management of severe spinal tuberculosis, with emphasis on the importance of timely intervention and multidisciplinary care.