Liquid biopsy-A biomarker‐based revolutionising technique in cancer therapy

Abstract Background and Aims Cancer has grabbed the attention of scientists and medical professionals all over the world much more than any other disease. In the past few decades, the medical field has improved quite a lot but progress in the path to find a solution for cancer is very less. As the p...

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Main Authors: Subham Sarkar (Author), Samraggi Chakraborty (Author), Soubhagya Ghosh (Author), Ekanansha Roy Chowdhury (Author), Jenifer Rajak (Author), Arup Kumar Mitra (Author), Ajoy Kumer (Author), Bikram Dhara (Author)
Format: Book
Published: Wiley, 2024-10-01T00:00:00Z.
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100 1 0 |a Subham Sarkar  |e author 
700 1 0 |a Samraggi Chakraborty  |e author 
700 1 0 |a Soubhagya Ghosh  |e author 
700 1 0 |a Ekanansha Roy Chowdhury  |e author 
700 1 0 |a Jenifer Rajak  |e author 
700 1 0 |a Arup Kumar Mitra  |e author 
700 1 0 |a Ajoy Kumer  |e author 
700 1 0 |a Bikram Dhara  |e author 
245 0 0 |a Liquid biopsy-A biomarker‐based revolutionising technique in cancer therapy 
260 |b Wiley,   |c 2024-10-01T00:00:00Z. 
500 |a 2768-0622 
500 |a 10.1002/ctd2.70006 
520 |a Abstract Background and Aims Cancer has grabbed the attention of scientists and medical professionals all over the world much more than any other disease. In the past few decades, the medical field has improved quite a lot but progress in the path to find a solution for cancer is very less. As the popularity of invasive technologies is diminishing in cancer treatment, scientists have come up withminimally invasive or non‐invasive alternatives, among which liquid biopsy, by far is the most suitable. Methods Liquid biopsy is used to analyse nucleic acids, subcellular components and circulating tumour cells in various biological fluids for diagnosis of cancer. It can also be used to know the efficacy of cancer drugs in a patient by analysing multiple samples. Outcomes Liquid biopsy is becoming standard of care as it allows biopsy of those samples in which solid tumour biopsies are not possible. The diversity of sampling procedures, such as collection of urine for urothelial carcinoma or bladder or prostate cancer and phlebotomy for other types of cancer, make liquid biopsy one of the best methods for diagnosis of cancer. Conclusion This review aims in discussing the several techniques used for the detection of cancer biomarkers and some clinical manifestations due to the changes in the biomarkers which are analysed by liquid biopsy. 
546 |a EN 
690 |a cancer biomarkers 
690 |a enzyme‐linked immunosorbent assay 
690 |a liquid biopsy 
690 |a next‐generation sequencing 
690 |a polymerase chain reaction 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Clinical and Translational Discovery, Vol 4, Iss 5, Pp n/a-n/a (2024) 
787 0 |n https://doi.org/10.1002/ctd2.70006 
787 0 |n https://doaj.org/toc/2768-0622 
856 4 1 |u https://doaj.org/article/c254018bbffc48a6bc310ef6189a1e8b  |z Connect to this object online.