In vitro glucose uptake by isolated rat hemi-diaphragm study of Aegle marmelos Correa root

The methanol extract of the root of Aegle marmelos, a medicinal plant, was fractionated into eight fractions using column chromatography. The anti-diabetic activity of all the fractions was studied using the glucose uptake by isolated rat hemi-diaphragm in vitro model. Using the bioassay-guided frac...

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Bibliographic Details
Main Authors: M. Rupeshkumar (Author), T. Balasubramanian (Author), T. Tamizmani (Author), Subban Ravi (Author), C.T. Sadashiva (Author), Indira Balachandran (Author)
Format: Book
Published: Bangladesh Pharmacological Society, 2009-06-01T00:00:00Z.
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Summary:The methanol extract of the root of Aegle marmelos, a medicinal plant, was fractionated into eight fractions using column chromatography. The anti-diabetic activity of all the fractions was studied using the glucose uptake by isolated rat hemi-diaphragm in vitro model. Using the bioassay-guided fractionation, two compounds 1 and 2 were isolated by column chromatography and identified as 6-methyl-4-chromanone and skimmianine respectively by NMR and mass spectral methods.
Item Description:1991-007X
1991-0088