Clinical relevance and discriminatory value of elevated liver aminotransferase levels for dengue severity.

• Main Authors: Linda K Lee (Author), Victor C Gan (Author), Vernon J Lee (Author), Adriana S Tan (Author), Yee Sin Leo (Author), David C Lye (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Elevation of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) is prominent in acute dengue illness. The World Health Organization (WHO) 2009 dengue guidelines defined AST or ALT ≥ 1000 units/liter (U/L) as a criterion for severe dengue. We aimed to assess the clinical...