Two-Dimensional and Spheroid-Based Three-Dimensional Cell Culture Systems: Implications for Drug Discovery in Cancer
The monolayer (two-dimensional or 2D) cell culture, while widely used, lacks fidelity in replicating vital cell interactions seen in vivo, leading to a shift toward three-dimensional (3D) models. Although monolayers offer simplicity and cost-effectiveness, spheroids mimic cellular environments bette...
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Main Authors: | Anali del Milagro Bernabe Garnique (Author), Natália Sudan Parducci (Author), Lívia Bassani Lins de Miranda (Author), Bruna Oliveira de Almeida (Author), Leonardo Sanches (Author), João Agostinho Machado-Neto (Author) |
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Format: | Book |
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MDPI AG,
2024-06-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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