Etiological role and molecular-genetic features of <i>Streptococcus pneumoniae</i> in children's infectious diseases
Objective: To study the etiological role, serotype distribution and prevalent Streptococcus pneumoniae genotypes (sequence types) in 459 children hospitalized with acute purulent otitis media, acute tonsillitis, community-acquired pneumonia, and purulent bacterial meningitis. Pneumococcal cultures i...
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| Format: | Book |
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LLC "Diagnostics and Vaccines",
2020-03-01T00:00:00Z.
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| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | doaj_c2b8f8d73b724ed58d68b7c34d0da6ed | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a I. N. Protasova |e author |
| 700 | 1 | 0 | |a G. P. Martynova |e author |
| 700 | 1 | 0 | |a N. A. Ilyenkova |e author |
| 700 | 1 | 0 | |a I. A. Kutischeva |e author |
| 700 | 1 | 0 | |a S. V. Domracheva |e author |
| 700 | 1 | 0 | |a O. P. Ovchinnikova |e author |
| 700 | 1 | 0 | |a E. S. Sokolovskaya |e author |
| 245 | 0 | 0 | |a Etiological role and molecular-genetic features of <i>Streptococcus pneumoniae</i> in children's infectious diseases |
| 260 | |b LLC "Diagnostics and Vaccines", |c 2020-03-01T00:00:00Z. | ||
| 500 | |a 2072-8107 | ||
| 500 | |a 10.22627/2072-8107-2020-19-1-7-12 | ||
| 520 | |a Objective: To study the etiological role, serotype distribution and prevalent Streptococcus pneumoniae genotypes (sequence types) in 459 children hospitalized with acute purulent otitis media, acute tonsillitis, community-acquired pneumonia, and purulent bacterial meningitis. Pneumococcal cultures isolated from patients were tested for sensitivity to antimicrobials, and presence of resistance genes.Materials and Methods: The cultural and molecular methods (PCR, sequencing) were used. Statistical analysis was carried out using Microsoft Excel 2007 and Statistica 6.0. Results: S. pneumoniae was detected in 16,8%. The prevalent serotypes were 19F (39.7%) and 19A (13.2%) - representatives of multidrug-resistant clonal com-plex 320. Isolates of serogroup 6 (6AB, 8.82%) belonged to clonal complex 315, and characterized by resistance to macrolides, clindamycin and tetracycline.From 70.6% to 88.2% of S. pneumoniae serotypes isolated from patients corresponded to «vaccine»-types. | ||
| 546 | |a RU | ||
| 690 | |a <i>streptococcus pneumoniae</i> | ||
| 690 | |a pneumococcus | ||
| 690 | |a etiological role | ||
| 690 | |a serotypes in children | ||
| 690 | |a sequence-types | ||
| 690 | |a resistance | ||
| 690 | |a Pediatrics | ||
| 690 | |a RJ1-570 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Детские инфекции (Москва), Vol 19, Iss 1, Pp 7-12 (2020) | |
| 787 | 0 | |n https://detinf.elpub.ru/jour/article/view/475 | |
| 787 | 0 | |n https://doaj.org/toc/2072-8107 | |
| 856 | 4 | 1 | |u https://doaj.org/article/c2b8f8d73b724ed58d68b7c34d0da6ed |z Connect to this object online. |