In vitro and in vivo characterization of domperidone-loaded fast dissolving buccal films

• 主要な著者: Gamal M. Zayed (著者), Saleh Abd-El Rasoul (著者), Mohamed A. Ibrahim (著者), Mohammed S. Saddik (著者), Doaa H. Alshora (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2020-03-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The delivery of drugs via fast dissolving films is an effective alternative for drugs with low bioavailability when administered by other routes. This is the case of domperidone (DMP) an anti-emetic drug with low water solubility and vulnerable to extensive first-pass effect. To overcome these limit...