The pathomorphological characteristics of clear-cell adenocarcinomas of the ovary and its mixed tumors with a clear-cell component

• Main Authors: M.. D Akhmedova (Author), M. A. Shabanov (Author), V. V. Barinov (Author), K. I. Zhordania (Author), L. I. Bokina (Author), E. A. Mustafina (Author)
• Format: Book
• Published: ABV-press, 2014-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 1994-4098; 1999-8627; 10.17650/1994-4098-2011-0-1-70-75
• Keywords: clear-cell ovarian adenocarcinomas; mixed malignant ovarian epithelial tumors with a clear-cell component; clinical and morphological signs; Gynecology and obstetrics; RG1-991
• Source: Опухоли женской репродуктивной системы, Vol 0, Iss 1, Pp 70-75 (2014)

Objective: to study the pathomorphological signs of pure and mixed clear-cell ovarian tumors with a clear-cell component.Subjects and methods. The clinical and morphological characteristics and the course of the disease were analyzed in 96 patients aged 21 to 75 years with clear-cell ovarian carcinoma. All the patients were divided into 2 groups: 1) 71 patients with pure clear-cell ovarian adenocarcinomas (COA) and 2) 25 patients with mixed malignant ovarian epithelial tumors (MMOET) with an obligatory clear-cell component. All pure forms of ovarian clear-cell malignancies were represented by adenocarcinoma in our study. This histologic type of the tumor was also prevalent among mixed ovarian neoplasms.Results. Clear, optically transparent cells and shoe nail-type (nail) ones were most common in COA. MMOETs showed moderate dif- ferentiation and malignancy and moderate atypia of a cell. Pure clear-cell neoplasms generally displayed 3 to 6 mitoses in 10 fields of vision whereas MMOET exhibited as many as 3 mitoses in 10 fields of vision.