Purpura fulminans following immediate bilateral breast reconstruction: A case report and literature review

Purpura fulminans (PF) is a rare, rapidly-progressive and life-threatening syndrome characterized by hypercoagulability that results in disseminated intravascular coagulation, microvascular thrombosis, and hemorrhagic infarction of the skin. Acute bacterial infection is the predominant etiology. The...

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Main Authors: Matthew R. Zeiderman (Author), Lauren M. Perry (Author), Anthony N. Almazan (Author), David G. Greenhalgh (Author), Tina L. Palmieri (Author)
Format: Book
Published: Elsevier, 2019-07-01T00:00:00Z.
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100 1 0 |a Matthew R. Zeiderman  |e author 
700 1 0 |a Lauren M. Perry  |e author 
700 1 0 |a Anthony N. Almazan  |e author 
700 1 0 |a David G. Greenhalgh  |e author 
700 1 0 |a Tina L. Palmieri  |e author 
245 0 0 |a Purpura fulminans following immediate bilateral breast reconstruction: A case report and literature review 
260 |b Elsevier,   |c 2019-07-01T00:00:00Z. 
500 |a 2468-9122 
500 |a 10.1016/j.burnso.2019.04.005 
520 |a Purpura fulminans (PF) is a rare, rapidly-progressive and life-threatening syndrome characterized by hypercoagulability that results in disseminated intravascular coagulation, microvascular thrombosis, and hemorrhagic infarction of the skin. Acute bacterial infection is the predominant etiology. The pathophysiology of PF results in extensive soft tissue necrosis with cutaneous wound depth mimicking full-thickness burns, limb gangrene requiring amputation, and multi-organ dysfunction syndrome. Consequently, mortality rate is over 50%. In the following case report, we present PF secondary to a complication of implant-based breast reconstruction following mastectomy. We review the management of PF and emphasize the importance of multidisciplinary management of this life-threatening illness. 
546 |a EN 
690 |a Dermatology 
690 |a RL1-803 
690 |a Medical emergencies. Critical care. Intensive care. First aid 
690 |a RC86-88.9 
655 7 |a article  |2 local 
786 0 |n Burns Open, Vol 3, Iss 3, Pp 108-111 (2019) 
787 0 |n http://www.sciencedirect.com/science/article/pii/S2468912219300161 
787 0 |n https://doaj.org/toc/2468-9122 
856 4 1 |u https://doaj.org/article/c2e29bf50d2d470e9b667bc60f91b8b5  |z Connect to this object online.