IL-1β Genetic Polimorphism in Menopause Women as Periodontal Disease Risk Factor
<p>Periodontal disease is a disease with multifactorial etiology that can occur in postmenopausal women. <strong>Objective:</strong> This research aims to know the description of the genetic polymorphism of IL-1β in postmenopausal women in Indonesia as a risk factor for periodontal...
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| Main Authors: | , |
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| Format: | Book |
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Faculty of Dentistry, Universitas Indonesia,
2013-05-01T00:00:00Z.
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| Summary: | <p>Periodontal disease is a disease with multifactorial etiology that can occur in postmenopausal women. <strong>Objective:</strong> This research aims to know the description of the genetic polymorphism of IL-1β in postmenopausal women in Indonesia as a risk factor for periodontal disease. <strong>Methods:</strong> This study is a descriptive study on 55 biological stored amples. Sample's extracted DNA was analysed for polymorphisms IL-1β+3954 using PCR-RFLP method with Taqα1 restriction enzyme digests then the result was electroforized. Research results were analyzed using chi square test. <strong>Results: </strong>The genotype CC frequency was 85.7%, CT 14.3%, and TT was absent in normal people. CC 86.5%, CT 8.3%, and TT did not exist in people who have periodontal disease. <strong>Conclusion: </strong>Genetic polymorphisms IL-1β in Indonesia's postmenopausal women is not a risk factor for periodontal disease</p><p>DOI: 10.14693/jdi.v18i1.52</p> |
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| Item Description: | 1693-9697 2355-4800 10.14693/jdi.v18i1.52 |