Anesthetic Isoflurane Posttreatment Attenuates Experimental Lung Injury by Inhibiting Inflammation and Apoptosis

• Main Authors: Jun-tang Li (Author), Hui Wang (Author), Wei Li (Author), Li-feng Wang (Author), Li-chao Hou (Author), Jing-lan Mu (Author), Xin Liu (Author), Hui-juan Chen (Author), Ke-lang Xie (Author), Nan-lin Li (Author), Chun-fang Gao (Author)
• Format: Book
• Published: Hindawi Limited, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We investigated the effect of 1.4% isoflurane (ISO) on the development of inflammation and apoptosis caused by zymosan (ZY) in mice. We found that ZY-challenged mice exhibited significant body weight loss, markedly high mortality, and significant lung injury characterized by the deterioration of his...