Exonic variants undergoing allele-specific selection in cancers
Abstract Background Allelic imbalance (AI) in tumors is caused by chromosomal and sub-chromosomal gains and losses. Results We evaluated AI at 109,086 germline exonic SNP loci in four cancer types, and identified a set of SNPs that demonstrate strong tumor allele specificity in AI events. Further an...
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| Main Authors: | , , , , , , , , , |
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| Format: | Book |
| Published: |
BMC,
2021-05-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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