ANALGETIC ACTIVITY OF SUBSTITUTED 1-(2-IMIDAZOLETHYL)-3- PYRROLINE-2-ONS

The article presents the review of initial stage of carried out studies of an analgetic activity of substituted 1-(2-imidazolethyl)-3-pyrroline-2-ons. We have established that compound marked with laboratory cipher as GKN-1165 at a dose of 50 mg/kg has analgetic activity close to the activity of eth...

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Main Authors: A. A. Ponomaryova (Author), A. S. Yurchenko (Author), N. N. Kasimova (Author)
Format: Book
Published: Volgograd State Medical University, Pyatigorsk Medical and Pharmaceutical Institute, 2015-09-01T00:00:00Z.
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100 1 0 |a A. A. Ponomaryova  |e author 
700 1 0 |a A. S. Yurchenko  |e author 
700 1 0 |a N. N. Kasimova  |e author 
245 0 0 |a ANALGETIC ACTIVITY OF SUBSTITUTED 1-(2-IMIDAZOLETHYL)-3- PYRROLINE-2-ONS 
260 |b Volgograd State Medical University, Pyatigorsk Medical and Pharmaceutical Institute,   |c 2015-09-01T00:00:00Z. 
500 |a 2307-9266 
500 |a 2413-2241 
500 |a 10.19163/2307-9266-2014-2-6(7)-99-101 
520 |a The article presents the review of initial stage of carried out studies of an analgetic activity of substituted 1-(2-imidazolethyl)-3-pyrroline-2-ons. We have established that compound marked with laboratory cipher as GKN-1165 at a dose of 50 mg/kg has analgetic activity close to the activity of ethanol of nimesulid comparison taken at the same dose. 
546 |a RU 
690 |a analgesic activity 
690 |a substituted 1-(2-imidazolethyl)-3-pyrroline-2-ons 
690 |a nimesulid 
690 |a hot-plate method. 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Фармация и фармакология (Пятигорск), Vol 2, Iss 6(7), Pp 99-101 (2015) 
787 0 |n https://www.pharmpharm.ru/jour/article/view/79 
787 0 |n https://doaj.org/toc/2307-9266 
787 0 |n https://doaj.org/toc/2413-2241 
856 4 1 |u https://doaj.org/article/c3987ca8f1664467b97512f90f19d6d0  |z Connect to this object online.