Toosendanin, a late-stage autophagy inhibitor, sensitizes triple-negative breast cancer to irinotecan chemotherapy

• Váldodahkkit: Shuang Zhang (Dahkki), Yu Dong (Dahkki), Xiuping Chen (Dahkki), Chris Soon Heng TAN (Dahkki), Min Li (Dahkki), Kai Miao (Dahkki), Jia-Hong Lu (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: BMC, 2022-05-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Abstract Background Triple-negative breast cancer (TNBC) is a highly aggressive subtype of breast cancer that develops resistance to chemotherapy frequently. Autophagy has been reported as a pro-survival response to chemotherapeutic drugs in TNBC, and suppression of autophagy can be a strategy to ov...