Risk of pneumonia in patients with insomnia: A nationwide population-based retrospective cohort study

• Main Authors: Chia-Ling Lin (Author), Ta-Chun Liu (Author), Chi-Hsiang Chung (Author), Wu-Chien Chien (Author)
• Format: Book
• Published: Elsevier, 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 1876-0341; 10.1016/j.jiph.2017.08.002
• Keywords: Infectious and parasitic diseases; RC109-216; Public aspects of medicine; RA1-1270
• Source: Journal of Infection and Public Health, Vol 11, Iss 2, Pp 270-274 (2018)

Evidence is lacking regarding whether insomnia increases the risk of infectious disease. Accordingly, the present study examined the risk of pneumonia in patients with insomnia.This study was a population-based retrospective cohort study on a cohort of 8061 patients with insomnia and a control cohort of 16,112 patients (matched by age, sex, and year of diagnosis) from the Taiwan National Health Insurance Research Database for the 2000-2010 period.Overall incidence of pneumonia was 50.6 per 1000 person-years in the insomnia cohort, which was significantly higher than that in the control cohort (30.9 per 1000 person-years). Overall, the insomnia cohort exhibited a higher risk of pneumonia (HR = 2.43; CI, 2.24-2.62). By age group, the risk of pneumonia was significantly higher in the insomnia cohort for those aged ≤40 years (HR = 3.23, CI: 1.38-7.57), 41-65 years (HR = 2.62, CI: 2.07-3.32), and >65 years (CI: 2.21-2.61).Compared with the controls, the insomnia cohort exhibited a higher risk of pneumonia, particularly in young adults. Keywords: Insomnia, Pneumonia, Retrospective cohort study, Infectious disease