High Infiltration of CD68+/CD163− Macrophages Is an Adverse Prognostic Factor after Neoadjuvant Chemotherapy in Esophageal and Gastric Adenocarcinoma

• Main Authors: Maria C. Svensson (Author), Maja Svensson (Author), Björn Nodin (Author), David Borg (Author), Charlotta Hedner (Author), Claes Hjalmarsson (Author), Karin Leandersson (Author), Karin Jirström (Author)
• Format: Book
• Published: Karger Publishers, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tumor-associated macrophages (TAMs) have emerged as key players in tumor immunology but demonstrate a continuum of functional states being either tumor suppressive or promoting. Moreover, chemotherapeutic agents have been shown to alter the tumor microenvironment. Perioperative chemotherapy is a sta...