A Comparison of Maternal and Fetal Outcomes of Pregnancies Complicated by Moderate to Severe Thrombocytopenia Caused by Gestational Thrombocytopenia Preeclampsia / HELLP Syndrome and Immune Thrombocytopenic Purpura

• Main Authors: Suna Özdemir (Author), Hüseyin Görkemli (Author), Ali Acar (Author), Çetin Çelik (Author), Erkan Kayıkçıoğlu (Author)
• Format: Book
• Published: Medical Network, 2008-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 1300-4751
• Keywords: Gestational thrombocytopenia, Preeclampsia/HELLP syndrome, Immune thrombocytopenic purpura, Fetal outcomes; Gynecology and obstetrics; RG1-991
• Source: Gynecology Obstetrics & Reproductive Medicine, Vol 14, Iss 3 (2008)

OBJECTIVE: Aim of this study was to compare obstetric risk factors and complications, and outcomes of pregnancies associated with moderate to severe thrombocytopenia caused by gestational thrombocytopenia (GT), preeclampsia/HELLP syndrome, and immune thrombocytopenic purpura (ITP). STUDY DESIGN: The study was composed of 135 women with a platelet count below 100.000/mm3. The characteristics and clinical details of all women and neonatal were recorded during their hospital course. RESULTS: The ratio of severe thrombocytopenia was observed significantly lower in GT group compared with preeclampsia / HELLP syndrome and ITP groups. Higher rates of oligohydroamnios, IUGR, and placental abruption were found among patients in preeclampsia+HELLP syndrome group. The rates of Apgar scores (<7) at 1 and 5 min, pH values (<7,2), and amniotic fluid with meconium were higher in preeclampsia / HELLP syndrome group. Neonatal thrombocytopenia was recorded in a total of 5 infants. CONCLUSION: The thrombocytopenia with preeclampsia/HELLP syndrome had less favorable obstetric and fetal outcomes.