Adrenal oncocytic pheochromocytoma with functionality in a neurofibromatosis patient: A case report
Background: There are 4 prior reports of oncocytic pheochromocytoma of the adrenal. It may histologically resemble cortical carcinoma, which also can have oncocytic cells. Case presentation: We report a 54-year-old male with neurofibromatosis 1 who had an endocrinologically functional, 13.5 cm tumor...
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| Main Authors: | , , |
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| Format: | Book |
| Published: |
Elsevier,
2018-06-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | Background: There are 4 prior reports of oncocytic pheochromocytoma of the adrenal. It may histologically resemble cortical carcinoma, which also can have oncocytic cells. Case presentation: We report a 54-year-old male with neurofibromatosis 1 who had an endocrinologically functional, 13.5 cm tumor. Histology showed mostly oncocytic cells. An adrenalectomy showed that the tumor had capsular and vascular invasion. Symptoms were cured by surgery. A cortical carcinoma with oncocytic change was initially favored, but the clinical history together with immunostain results were consistent with pheochromocytoma with oncocytic change. Conclusions: In conclusion, the clinical history was crucial to the diagnosis. This is the first tumor of this type in a neurofibromatosis patient and the first in which functional effects were caused. |
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| Item Description: | 2214-3300 10.1016/j.ehpc.2018.02.002 |