Adrenal oncocytic pheochromocytoma with functionality in a neurofibromatosis patient: A case report
Background: There are 4 prior reports of oncocytic pheochromocytoma of the adrenal. It may histologically resemble cortical carcinoma, which also can have oncocytic cells. Case presentation: We report a 54-year-old male with neurofibromatosis 1 who had an endocrinologically functional, 13.5 cm tumor...
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| Format: | Book |
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Elsevier,
2018-06-01T00:00:00Z.
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| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | doaj_c4a56f18b95f45d1a3a8efca0c47f809 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Kenneth A. Iczkowski, MD |e author |
| 700 | 1 | 0 | |a Douglas B. Evans, MD |e author |
| 700 | 1 | 0 | |a Saul M. Suster, MD |e author |
| 245 | 0 | 0 | |a Adrenal oncocytic pheochromocytoma with functionality in a neurofibromatosis patient: A case report |
| 260 | |b Elsevier, |c 2018-06-01T00:00:00Z. | ||
| 500 | |a 2214-3300 | ||
| 500 | |a 10.1016/j.ehpc.2018.02.002 | ||
| 520 | |a Background: There are 4 prior reports of oncocytic pheochromocytoma of the adrenal. It may histologically resemble cortical carcinoma, which also can have oncocytic cells. Case presentation: We report a 54-year-old male with neurofibromatosis 1 who had an endocrinologically functional, 13.5 cm tumor. Histology showed mostly oncocytic cells. An adrenalectomy showed that the tumor had capsular and vascular invasion. Symptoms were cured by surgery. A cortical carcinoma with oncocytic change was initially favored, but the clinical history together with immunostain results were consistent with pheochromocytoma with oncocytic change. Conclusions: In conclusion, the clinical history was crucial to the diagnosis. This is the first tumor of this type in a neurofibromatosis patient and the first in which functional effects were caused. | ||
| 546 | |a EN | ||
| 690 | |a Oncocytic | ||
| 690 | |a Pheochromocytoma | ||
| 690 | |a Adrenal | ||
| 690 | |a Functional | ||
| 690 | |a Pathology | ||
| 690 | |a RB1-214 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Human Pathology: Case Reports, Vol 12, Iss C, Pp 39-41 (2018) | |
| 787 | 0 | |n http://www.sciencedirect.com/science/article/pii/S2214330018300051 | |
| 787 | 0 | |n https://doaj.org/toc/2214-3300 | |
| 856 | 4 | 1 | |u https://doaj.org/article/c4a56f18b95f45d1a3a8efca0c47f809 |z Connect to this object online. |