A method for measuring mitochondrial DNA copy number in pediatric populations

• Main Authors: Simran Maggo (Author), Liam Y. North (Author), Aime Ozuna (Author), Dejerianne Ostrow (Author), Yander R. Grajeda (Author), Hesamedin Hakimjavadi (Author), Jennifer A. Cotter (Author), Alexander R. Judkins (Author), Pat Levitt (Author), Xiaowu Gai (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The mitochondrion is a multifunctional organelle that modulates multiple systems critical for homeostasis during pathophysiological stress. Variation in mitochondrial DNA (mtDNA) copy number (mtDNAcn), a key mitochondrial change associated with chronic stress, is an emerging biomarker for disease pa...