A novel oral medicated jelly for enhancement of etilefrine hydrochloride bioavailability: In vitro characterization and pharmacokinetic evaluation in healthy human volunteers
Etilefrine hydrochloride (ET) is a water-soluble drug that is used to treat hypotension, but it has a bitter taste and low bioavailability due to undergoing the first-pass effect. Thus, this study aimed to develop and evaluate oral medicated jelly (OMJ) containing ET that could offer an easily taken...
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Main Authors: | Ahmed Hassen Elshafeey (Author), Rania Moataz El-Dahmy (Author) |
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Format: | Book |
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Elsevier,
2022-10-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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