Interleukin-1β-Induced Senescence Promotes Osteoblastic Transition of Vascular Smooth Muscle Cells

• Main Authors: Linzi Han (Author), Yuying Zhang (Author), Mingming Zhang (Author), Liyu Guo (Author), Jun Wang (Author), Fanjun Zeng (Author), Deping Xu (Author), Zongzhi Yin (Author), Yuanhong Xu (Author), Deguang Wang (Author), Haisheng Zhou (Author)
• Format: Book
• Published: Karger Publishers, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Interleukin (IL)-1β, as a key biomarker and mediator of vascular calcification in patients with end-stage renal disease (ESRD), may be involved in the process of premature senescence of vascular smooth muscle cells (VSMCs). This work sought to investigate whether IL-1β-induced prematur...