Sperm histone H3 lysine 4 tri-methylation serves as a metabolic sensor of paternal obesity and is associated with the inheritance of metabolic dysfunction
Objective: Parental environmental exposures can strongly influence descendant risks for adult disease. How paternal obesity changes the sperm chromatin leading to the acquisition of metabolic disease in offspring remains controversial and ill-defined. The objective of this study was to assess (1) wh...
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Main Authors: | Anne-Sophie Pepin (Author), Christine Lafleur (Author), Romain Lambrot (Author), Vanessa Dumeaux (Author), Sarah Kimmins (Author) |
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Format: | Book |
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Elsevier,
2022-05-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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