Preparation, characterization, in vitro drug release and anti-inflammatory of thymoquinone-loaded chitosan nanocomposite

• Main Authors: Mothanna Sadiq Al-Qubaisi (Author), Ashwaq Shakir Al-Abboodi (Author), Fatah H. Alhassan (Author), Samer Hussein- (Author), Moayad Husein Flaifel (Author), Eltayeb E.M. Eid (Author), Hussah Abdullah Alshwyeh (Author), Mohd Zobir Hussein (Author), Sulaiman Mohammed Alnasser (Author), Mohammed Ibrahim Saeed (Author), Abdullah Rasedee (Author), Wisam Nabeel Ibrahim (Author)
• Format: Book
• Published: Elsevier, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this study, we formulated Thymoquinone-loaded nanocomposites (TQ-NCs) using high-pressure homogenizer without sodium tripolyphosphate. The TQ-NCs were characterized and their anti-inflammatory determined by the response of the LPS-stimulated macrophage RAW 264.7 cells in the production of nitric...