Targeted Metabolomics Highlights Dramatic Antioxidant Depletion, Increased Oxidative/Nitrosative Stress and Altered Purine and Pyrimidine Concentrations in Serum of Primary Myelofibrosis Patients

• 主要な著者: Renata Mangione (著者), Cesarina Giallongo (著者), Andrea Duminuco (著者), Enrico La Spina (著者), Lucia Longhitano (著者), Sebastiano Giallongo (著者), Daniele Tibullo (著者), Giuseppe Lazzarino (著者), Miriam Wissam Saab (著者), Arianna Sbriglione (著者), Giuseppe A. Palumbo (著者), Andrea Graziani (著者), Amer M. Alanazi (著者), Valentina Di Pietro (著者), Barbara Tavazzi (著者), Angela Maria Amorini (著者), Giacomo Lazzarino (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2024-04-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

To date, little is known concerning the circulating levels of biochemically relevant metabolites (antioxidants, oxidative/nitrosative stress biomarkers, purines, and pyrimidines) in patients with primary myelofibrosis (PMF), a rare form of myeloproliferative tumor causing a dramatic decrease in eryt...