New Technology of Thermoplastic Coating for Osmotic Pump Tablets: Study on in vivo Drug Release

• Main Authors: Chun Ping Yuan (Author), Hui Min Hou (Author), Zhi Hong Cheng (Author), Qing Hua Ge (Author), Ding Zhong Song (Author), Jian Qiang Xi (Author)
• Format: Book
• Published: Georg Thieme Verlag KG, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aim The in vivo pharmacokinetics of thermoplastic-coated tablets prepared by a new technology of thermoplastic coating in Beagle dogs were studied, and the correlation between in vitro release and in vivo absorption was analyzed. Methods The in vitro release profiles of metformin hydrochloride therm...