Fam96a is essential for the host control of Toxoplasma gondii infection by fine-tuning macrophage polarization via an iron-dependent mechanism.

• Main Authors: Zhuanzhuan Liu (Author), Hanying Wang (Author), Zhiwei Zhang (Author), Yulu Ma (Author), Qiyue Jing (Author), Shenghai Zhang (Author), Jinzhi Han (Author), Junru Chen (Author), Yaoyao Xiang (Author), Yanbo Kou (Author), Yanxia Wei (Author), Lu Wang (Author), Yugang Wang (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Toxoplasmosis affects a quarter of the world's population. Toxoplasma gondii (T.gondii) is an intracellular parasitic protozoa. Macrophages are necessary for proliferation and spread of T.gondii by regulating immunity and metabolism. Family with sequence similarit...