Ribosome Assembly as Antimicrobial Target

• Main Authors: Rainer Nikolay (Author), Sabine Schmidt (Author), Renate Schlömer (Author), Elke Deuerling (Author), Knud H. Nierhaus (Author)
• Format: Book
• Published: MDPI AG, 2016-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Many antibiotics target the ribosome and interfere with its translation cycle. Since translation is the source of all cellular proteins including ribosomal proteins, protein synthesis and ribosome assembly are interdependent. As a consequence, the activity of translation inhibitors might indirectly...