Protease activated receptors 1 and 4 sensitize TRPV1 in nociceptive neurones

• Main Authors: Magherini Pier C (Author), Reeh Peter (Author), Hechtfischer Sabine C (Author), Prandini Massimiliano (Author), Kinsey Anna M (Author), Vellani Vittorio (Author), Giacomoni Chiara (Author), McNaughton Peter A (Author)
• Format: Book
• Published: SAGE Publishing, 2010-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Protease-activated receptors (PAR1-4) are activated by proteases released by cell damage or blood clotting, and are known to be involved in promoting pain and hyperalgesia. Previous studies have shown that PAR2 receptors enhance activation of TRPV1 but the role o...