Could Toxomplasma gondii infection be dangerous? - Systematic review

Introduction:  Toxoplasma gondii is an intracellular protozoan commonly found in humans in the form of three main forms: tachyzoite, tissue cyst and oocyst. The definitive host is the Felidae family, and one of the intermediate hosts is humans. The most common routes of infection are ingestion of ra...

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Main Authors: Gabriela Frącz (Author), Klaudia Kuliga (Author), Marcin Kuliga (Author), Kinga Musz (Author), Agnieszka Socha (Author), Kinga Śnieżek (Author)
Format: Book
Published: Kazimierz Wielki University, 2023-08-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Gabriela Frącz  |e author 
700 1 0 |a Klaudia Kuliga  |e author 
700 1 0 |a Marcin Kuliga  |e author 
700 1 0 |a Kinga Musz  |e author 
700 1 0 |a Agnieszka Socha  |e author 
700 1 0 |a Kinga Śnieżek  |e author 
245 0 0 |a Could Toxomplasma gondii infection be dangerous? - Systematic review 
260 |b Kazimierz Wielki University,   |c 2023-08-01T00:00:00Z. 
500 |a 10.12775/JEHS.2023.34.01.009 
500 |a 2391-8306 
520 |a Introduction:  Toxoplasma gondii is an intracellular protozoan commonly found in humans in the form of three main forms: tachyzoite, tissue cyst and oocyst. The definitive host is the Felidae family, and one of the intermediate hosts is humans. The most common routes of infection are ingestion of raw or undercooked meat, water and food contaminated with oocysts. Among the forms of infection, we distinguish between the acquired form and the much more dangerous congenital form. Aim of the study: The objective of the study was to rewiev the literature describing the dangerous impact of Toxoplasma gondii infection on human. Methods and materials: : We reviewed the literature available in the PubMed database, using the key words: "toxoplasma gondii"; "congenital toxoplasmosis"; "pregnacy". Results: T. gondii infection is particularly dangerous in pregnant women, due to the high risk of vertical transmission of the infection to the developing fetus. The clinical presentation of congenital toxoplasmosis depends on the gestational age at which the infection occurred. Pathognomonic signs of congenital toxoplasmosis include Sabin-Pinkerton Triad, which includes inflammation of the retina and choroid of the eye, dilatation of the brain's ventricular system and intracranial calcifications. Available pharmacotherapy works on tachyzoites present in the initial phase of acquired infection, congenital infection and reactivated infection in immunodeficient patients, available drugs do not work on tissue cysts. Conclusion: The consequences of Toxoplasma gondii infection are particularly dangerous for the fetus, so pregnant women should pay special attention to hand hygiene and thorough washing of the food they eat. For this reason, it is extremely important to educate pregnant women about health issues and draw attention to the possible consequences of T.gondii infection. 
546 |a EN 
546 |a ES 
546 |a PL 
546 |a RU 
546 |a UK 
690 |a toxoplasmosis 
690 |a toxoplasma gondii 
690 |a congenital toxoplasmosis 
690 |a pregnacy 
690 |a Education 
690 |a L 
690 |a Sports 
690 |a GV557-1198.995 
690 |a Medicine 
690 |a R 
655 7 |a article  |2 local 
786 0 |n Journal of Education, Health and Sport, Vol 34, Iss 1 (2023) 
787 0 |n https://apcz.umk.pl/JEHS/article/view/44886 
787 0 |n https://doaj.org/toc/2391-8306 
856 4 1 |u https://doaj.org/article/c5bc3d6f7b5044d3a0d5efdb44e622cd  |z Connect to this object online.