A review on botanicals with wound healing activity for pemphigus vulgaris: perspective of traditional Persian medicine and conventional medicine

Objective: As a rare autoimmune disease, pemphigus vulgaris has a poor prognosis especially in lack of proper medical support. This blistering disease involves both the skin and mucus membranes. The challenge is improving the healing process of skin lesions of which, superimposed infections are amon...

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Main Authors: Fatemeh Atarzadeh (Author), Amir Mohammad Jaladat (Author), Babak Daneshfard (Author), Ladan Dastgheib (Author), Mohammad Kamalinejad (Author), Gholamreza Amin (Author)
Format: Book
Published: Mashhad University of Medical Sciences, 2017-10-01T00:00:00Z.
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001 doaj_c61783c5567c46f1bbd1525752a8d08d
042 |a dc 
100 1 0 |a Fatemeh Atarzadeh  |e author 
700 1 0 |a Amir Mohammad Jaladat  |e author 
700 1 0 |a Babak Daneshfard  |e author 
700 1 0 |a Ladan Dastgheib  |e author 
700 1 0 |a Mohammad Kamalinejad  |e author 
700 1 0 |a Gholamreza Amin  |e author 
245 0 0 |a A review on botanicals with wound healing activity for pemphigus vulgaris: perspective of traditional Persian medicine and conventional medicine 
260 |b Mashhad University of Medical Sciences,   |c 2017-10-01T00:00:00Z. 
500 |a 2228-7930 
500 |a 2228-7949 
500 |a 10.22038/ajp.2017.17889.1695 
520 |a Objective: As a rare autoimmune disease, pemphigus vulgaris has a poor prognosis especially in lack of proper medical support. This blistering disease involves both the skin and mucus membranes. The challenge is improving the healing process of skin lesions of which, superimposed infections are among the main causes of the disease mortality. Accordingly, we aimed to assess the treatment options suggested by traditional Persian medicine (TPM) and compare them with current findings. Materials and Methods: We studied the main clinical and pharmaceutical textbooks of TPM   (Kitāb al-hāwīfī al-tibb, the Canon of Medicine, Eksir-e-Aazam, Tuhfat al-mu'minīn, Makhzan al-adviyah (focusing on the skin chapter and respective herbal remedies for the inflamed skin and ulcers. Additionally, scientific databases such as PubMed, Science direct, Scopus, and Google Scholar were searched for the current pharmacological evidence. In the studied books, the term "hot ulcers" was found close to what is known as "Pemphigus vulgaris". Results: Reported medicinal herbs possess anti-inflammatory, antioxidant, wound healing, and antibacterial activities reported by recent studies. Therefore, they could be introduced as novel natural remedies for pemphigoid wounds. Conclusion: Taken as a whole, the review of traditional remedies for hot ulcers in Persian medical and pharmaceutical literature may open a new window toward developing new topical treatments for this disease. 
546 |a EN 
690 |a Pemphigus vulgaris 
690 |a Traditional Persian Medicine 
690 |a Herbal remedies 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Avicenna Journal of Phytomedicine, Vol 7, Iss 6, Pp 486-494 (2017) 
787 0 |n http://ajp.mums.ac.ir/article_8261_d29eea9e3b30e5040af2ef15d3b55269.pdf 
787 0 |n https://doaj.org/toc/2228-7930 
787 0 |n https://doaj.org/toc/2228-7949 
856 4 1 |u https://doaj.org/article/c61783c5567c46f1bbd1525752a8d08d  |z Connect to this object online.