Effects of combined ciprofloxacin and Neulasta therapy on intestinal pathology and gut microbiota after high-dose irradiation in mice

• Main Authors: Timothy S. Horseman (Author), Andrew M. Frank (Author), Georgetta Cannon (Author), Min Zhai (Author), Matthew G. Olson (Author), Bin Lin (Author), Xianghong Li (Author), Lisa Hull (Author), Mang Xiao (Author), Juliann G. Kiang (Author), David M. Burmeister (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

IntroductionTreatments that currently exist in the strategic national stockpile for acute radiation syndrome (ARS) focus on the hematopoietic subsyndrome, with no treatments on gastrointestinal (GI)-ARS. While the gut microbiota helps maintain host homeostasis by mediating GI epithelial and mucosal...