Squamous cell carcinoma arising from chronic osteomyelitis massively expanding into the medullary cavity: A case report

An 80-year-old man was diagnosed with squamous cell carcinoma (SCC) arising from chronic osteomyelitis in his right femur. The pathological findings of the amputated leg showed ulcerated tumor extending from the skin to the medullary cavity of the right femur in a continuous fashion. Metastasis in t...

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Auteurs principaux: Taisei Kurihara (Auteur), Yoshiyuki Suehara (Auteur), Keisuke Akaike (Auteur), Takuo Hayashi (Auteur), Taketo Okubo (Auteur), Youngji Kim (Auteur), Tatsuya Takagi (Auteur), Kazuo Kaneko (Auteur), Takashi Yao (Auteur), Tsuyoshi Saito (Auteur)
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Publié: Elsevier, 2019-06-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Taisei Kurihara  |e author 
700 1 0 |a Yoshiyuki Suehara  |e author 
700 1 0 |a Keisuke Akaike  |e author 
700 1 0 |a Takuo Hayashi  |e author 
700 1 0 |a Taketo Okubo  |e author 
700 1 0 |a Youngji Kim  |e author 
700 1 0 |a Tatsuya Takagi  |e author 
700 1 0 |a Kazuo Kaneko  |e author 
700 1 0 |a Takashi Yao  |e author 
700 1 0 |a Tsuyoshi Saito  |e author 
245 0 0 |a Squamous cell carcinoma arising from chronic osteomyelitis massively expanding into the medullary cavity: A case report 
260 |b Elsevier,   |c 2019-06-01T00:00:00Z. 
500 |a 2214-3300 
500 |a 10.1016/j.ehpc.2019.01.008 
520 |a An 80-year-old man was diagnosed with squamous cell carcinoma (SCC) arising from chronic osteomyelitis in his right femur. The pathological findings of the amputated leg showed ulcerated tumor extending from the skin to the medullary cavity of the right femur in a continuous fashion. Metastasis in the left clavicle was also noticed 6 months after surgery, and the patient ultimately died 8 months after the operation. A review of the previous literature showed that SCCs arising from chronic osteomyelitis which widely extended to the bone marrow are quite rare. A careful pathological evaluation, such as cytological examination from bone marrow washing, might be necessary and useful for early detection of malignant neoplasms arising from osteomyelitis, although not performed in this case. Keywords: Osteomyelitis, Squamous cell carcinoma, Malignant transformation 
546 |a EN 
690 |a Pathology 
690 |a RB1-214 
655 7 |a article  |2 local 
786 0 |n Human Pathology: Case Reports, Vol 16, Iss , Pp - (2019) 
787 0 |n http://www.sciencedirect.com/science/article/pii/S221433001830107X 
787 0 |n https://doaj.org/toc/2214-3300 
856 4 1 |u https://doaj.org/article/c625df6bc8ef44d0a55af0799f1e0189  |z Connect to this object online.