Brain-derived neurotrophic factor is required for axonal growth of selective groups of neurons in the arcuate nucleus

• Main Authors: Guey-Ying Liao (Author), Karine Bouyer (Author), Anna Kamitakahara (Author), Niaz Sahibzada (Author), Chien-Hua Wang (Author), Michael Rutlin (Author), Richard B. Simerly (Author), Baoji Xu (Author)
• Format: Knjiga
• Izdano: Elsevier, 2015-06-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Objective: Brain-derived neurotrophic factor (BDNF) is a potent regulator of neuronal development, and the Bdnf gene produces two populations of transcripts with either a short or long 3' untranslated region (3' UTR). Deficiencies in BDNF signaling have been shown to cause severe obesity i...