Protective and enhancing HLA alleles, HLA-DRB1*0901 and HLA-A*24, for severe forms of dengue virus infection, dengue hemorrhagic fever and dengue shock syndrome.

• Main Authors: Thi Phuong Lan Nguyen (Author), Mihoko Kikuchi (Author), Thi Que Huong Vu (Author), Quang Ha Do (Author), Thi Thuy Tran (Author), Dinh Tham Vo (Author), Manh Tuan Ha (Author), Van Tuong Vo (Author), Thi Phi Nga Cao (Author), Van Dat Tran (Author), Toshifumi Oyama (Author), Kouichi Morita (Author), Michio Yasunami (Author), Kenji Hirayama (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2008-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Dengue virus (DV) infection is one of the most important mosquito-borne diseases in the tropics. Recently, the severe forms, dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS), have become the leading cause of death among children in Southern Vietnam. Protective and/or pathog...