Smart pH- and Temperature-Sensitive Micelles Based on Chitosan Grafted with Fatty Acids to Increase the Efficiency and Selectivity of Doxorubicin and Its Adjuvant Regarding the Tumor Cells

• Автори: Igor D. Zlotnikov (Автор), Dmitriy A. Streltsov (Автор), Alexander A. Ezhov (Автор), Elena V. Kudryashova (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2023-04-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

The main factors that determine the low effectiveness of chemotherapy are the low target bioavailability of antitumor drugs and the efflux process. In attempts to overcome this problem, several approaches are proposed here. Firstly, the development of polymeric micellar systems based on chitosan gra...