Ex vivo innate immune cytokine signature of enhanced risk of relapsing brucellosis.

• Main Authors: Kristyn E Feldman (Author), Paul M Loriaux (Author), Mayuko Saito (Author), Iskra Tuero (Author), Homarh Villaverde (Author), Tenaya Siva (Author), Eduardo Gotuzzo (Author), Robert H Gilman (Author), Alexander Hoffmann (Author), Joseph M Vinetz (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Brucellosis, a zoonotic infection caused by one of the Gram-negative intracellular bacteria of the Brucella genus, is an ongoing public health problem in Perú. While most patients who receive standard antibiotic treatment recover, 5-40% suffer a brucellosis relapse. In this study, we examined the e...