A Novel Single-Strand RNAi Therapeutic Agent Targeting the (Pro)renin Receptor Suppresses Ocular Inflammation
The receptor-associated prorenin system (RAPS) refers to the pathogenic mechanism whereby prorenin binding to the (pro)renin receptor [(P)RR] dually activates the tissue renin-angiotensin system (RAS) and RAS-independent intracellular signaling. Here we revealed significant upregulation of prorenin...
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Main Authors: | Atsuhiro Kanda (Author), Erdal Tan Ishizuka (Author), Atsushi Shibata (Author), Takahiro Matsumoto (Author), Hidekazu Toyofuku (Author), Kousuke Noda (Author), Kenichi Namba (Author), Susumu Ishida (Author) |
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Format: | Book |
Published: |
Elsevier,
2017-06-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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