High Glucose Concentration Impairs 5-PAHSA Activity by Inhibiting AMP-Activated Protein Kinase Activation and Promoting Nuclear Factor-Kappa-B-Mediated Inflammation

Recently, the endogenous fatty acid palmitic acid-5-hydroxystearic acid (5-PAHSA) was found to increase insulin sensitivity and have anti-inflammatory effects in mice with high-fat diet (HFD)-induced diabetes. However, it is unknown if 5-PAHSA affects glucose and lipid metabolism in db/db mice, whic...

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Bibliographic Details
Main Authors: Yan-Mei Wang (Author), Hong-Xia Liu (Author), Ning-Yuan Fang (Author)
Format: Book
Published: Frontiers Media S.A., 2019-01-01T00:00:00Z.
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