Effect of 3-subsitution of quinolinehydroxamic acids on selectivity of histone deacetylase isoforms
A series of 3-subsituted quinolinehydroxamic acids has been synthesised and evaluated for their effect on human lung cancer cell line (A549), human colorectal cancer cell line (HCT116) and HDAC isoforms 1, 2, 6, and 8. The results indicated that substitution at C3 of quinoline is favoured for HDAC6...
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| Main Authors: | , , , , , , |
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| Format: | Book |
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Taylor & Francis Group,
2021-01-01T00:00:00Z.
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