Antibiofilm Evaluation of Two Different Denture Liners Incorporated with Zirconium Oxide Nanoparticles
Abstract Objectives: This in vitro study was purposed to examine the effects of incorporation nano-ZrO2 on antibiofilm activity, glucose sorption, weight change, and surface roughness of two different types of denture liners. Materials and Methods: Modified nano-ZrO2 were added to silicone-based and...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Bog |
| Udgivet: |
Cumhuriyet University,
2022-03-01T00:00:00Z.
|
| Fag: | |
| Online adgang: | Connect to this object online. |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|
| Summary: | Abstract Objectives: This in vitro study was purposed to examine the effects of incorporation nano-ZrO2 on antibiofilm activity, glucose sorption, weight change, and surface roughness of two different types of denture liners. Materials and Methods: Modified nano-ZrO2 were added to silicone-based and acrylic resin-based prosthetic lining materials at two different concentrations (0.5% and 1%). The antibiofilm potentials of test groups against Candida albicans (C. albicans), Staphylococcus aureus (S. aureus), and Streptococcus mutans (S. mutans) were determined using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium (MTT) method. Surface roughness, weight change, and glucose sorption of denture liners were also evaluated after modifying with nano-ZrO2. Results: According to the antibiofilm activity results, 1% nano-ZrO2 addition to silicon-based and acrylic resin-based denture liners resulted in 16.48% and 13.39% of biofilm inhibition for S. aureus, respectively. 1% nano-ZrO2 addition to silicon-based denture liners also inhibited the S. mutans biofilm formation at an 8.16% rate. Nano-ZrO2 addition to the test groups had no inhibition effect on C. albicans biofilm formation. Surface roughness decreased significantly once nano-ZrO2 was added in tissue conditioner test groups (p=0.012), however, the addition of 0.5% nano-ZrO2 increased soft denture liner test group significantly (p<0.001). Conclusions: To overcome the microbial biofilm problems (especially against S. aureus and S. mutans) caused by the use of denture liners, addition of nano-ZrO2 might be a promising agent with its antibiofilm capacities. |
|---|---|
| Emne beskrivelse: | 1302-5805 2146-2852 10.7126/cumudj.970931 |