The effectiveness of first-generation antihistamines in the treatment of allergic diseases in children

The article presents modern information on the clini­cal application, effectiveness and safety of the first-generation H1-antihistamine - dimetindene maleate. A brief description of the drug is given, the main indicators of its pharmacokinetics and pharmacodynamics are described. The attention is fo...

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Bibliographic Details
Main Authors: A.E. Abaturov (Author), E.L. Krivusha (Author), E.A. Agafonova (Author), N.M. Tokarevа (Author), V.L. Babich (Author)
Format: Book
Published: Zaslavsky O.Yu., 2018-05-01T00:00:00Z.
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100 1 0 |a A.E. Abaturov  |e author 
700 1 0 |a E.L. Krivusha  |e author 
700 1 0 |a E.A. Agafonova  |e author 
700 1 0 |a N.M. Tokarevа  |e author 
700 1 0 |a V.L. Babich  |e author 
245 0 0 |a The effectiveness of first-generation antihistamines in the treatment of allergic diseases in children 
260 |b Zaslavsky O.Yu.,   |c 2018-05-01T00:00:00Z. 
500 |a 2224-0551 
500 |a 2307-1168 
500 |a 10.22141/2224-0551.13.4.2018.137026 
520 |a The article presents modern information on the clini­cal application, effectiveness and safety of the first-generation H1-antihistamine - dimetindene maleate. A brief description of the drug is given, the main indicators of its pharmacokinetics and pharmacodynamics are described. The attention is focused on the main pharmacological mechanisms of the clinical effects of the drug. An analysis of the results of clinical studies using dimetindene maleate in allergic and infectious diseases of the skin in children has been carried out. A brief description is given of the drug Phenokit appeared on the pharmaceutical market of Ukraine, the main indications for its administration are substantiated. 
546 |a EN 
546 |a UK 
690 |a children 
690 |a allergic diseases 
690 |a atopic dermatitis 
690 |a H1-antihistamines 
690 |a treatment 
690 |a Pediatrics 
690 |a RJ1-570 
655 7 |a article  |2 local 
786 0 |n Zdorovʹe Rebenka, Vol 13, Iss 4, Pp 394-400 (2018) 
787 0 |n http://childshealth.zaslavsky.com.ua/article/view/137026 
787 0 |n https://doaj.org/toc/2224-0551 
787 0 |n https://doaj.org/toc/2307-1168 
856 4 1 |u https://doaj.org/article/c7ef865bee2a4f9986a22fb0182b9dc8  |z Connect to this object online.