Cover Image

Jianpi Yangzheng Xiaozheng decoction alleviates gastric cancer progression via suppressing exosomal PD-L1

Jianpi Yangzheng Xiaozheng decoction (JPYZXZ) is an empirical traditional Chinese medicine formula that has been reported to significantly prolong the survival of patients with advanced gastric cancer (GC). However, its underlying mechanism have not been fully elucidated. The present work aims to ex...

Full description

Saved in:

Bibliographic Details
Main Authors:	Yanzhen Chen (Author), Jiayun Liu (Author), Yuxuan Chen (Author), Ruijuan Zhang (Author), Jialei Tao (Author), Xu Chen (Author), Haidan Wang (Author), Qingmin Sun (Author), Jian Wu (Author), Shenlin Liu (Author)
Format:	Book
Published:	Frontiers Media S.A., 2023-08-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Qianlie Xiaozheng Decoction Induces Autophagy in Human Prostate Cancer Cells via Inhibition of the Akt/mTOR Pathway
by: Yuehua Xu, et al.
Published: (2018)

Therapeutic Effect and Mechanism of Bushen-Jianpi-Jiedu Decoction Combined with Chemotherapeutic Drugs on Postoperative Colorectal Cancer
by: Meng-Die Yang, et al.
Published: (2021)

Jianpi Huayu Decoction enhances the effect of sorafenib and alleviates adverse events in hepatocellular carcinoma by remodeling the gut microbiota
by: Xue Deng, et al.
Published: (2022)

Jianpi Yangwei decoction promotes apoptosis and suppresses proliferation of 5-fluorouracil resistant gastric cancer cells in vitro and in vivo
by: Huijuan Tang, et al.
Published: (2020)

Jianpi Jieyu Decoction, An Empirical Herbal Formula, Exerts Psychotropic Effects in Association With Modulation of Gut Microbial Diversity and GABA Activity
by: Lanying Liu, et al.
Published: (2021)

Jianpi Qinghua Fomula alleviates insulin resistance via restraining of MAPK pathway to suppress inflammation of the small intestine in DIO mice
by: Yahua Liu, et al.
Published: (2022)

Yiwei decoction promotes apoptosis of gastric cancer cells through spleen-derived exosomes
by: Yingzhi Chen, et al.
Published: (2023)

Knockdown and Overexpression Experiments to Investigate the Inhibitory Mechanism of Fuzheng Xiaozheng Prescription, an Effective Chinese Herbal Formula for the Clinical Treatment of Hepatocellular Carcinoma
by: Xia Li, et al.
Published: (2024)

Jianpi-yangwei decoction inhibits DNA damage repair in the drug resistance of gastric cancer by reducing FEN1 expression
by: Wenjie Huang, et al.
Published: (2020)

The Extracellular Matrix Enriched With Exosomes for the Treatment on Pulmonary Fibrosis in Mice
by: Yanzhen Yu, et al.
Published: (2021)

Antiaging effect of a Jianpi-yangwei formula in Caenorhabditis elegans
by: Liling Zeng, et al.
Published: (2019)

The immunomodulatory effects of Qushi Jianpi Hewei Decoction (QJHD) for patients with COVID-19 by metagenomics and transcriptomic sequencing
by: Jinhui Li, et al.
Published: (2022)

The Effects of Erchen Decoction on Gut Microbiota and Lipid Metabolism Disorders in Zucker Diabetic Fatty Rats
by: Tian Zhao, et al.
Published: (2021)

Adjuvant therapy with Jianpi Huayu decoction improves overall and recurrence-free survival after hepatectomy for hepatocellular carcinoma: a retrospective propensity score-matching study
by: Rui Luo, et al.
Published: (2023)

Jianpi Huayu Decoction Attenuates the Immunosuppressive Status of H22 Hepatocellular Carcinoma-Bearing Mice: By Targeting Myeloid-Derived Suppressor Cells
by: Yingjie Xie, et al.
Published: (2020)

Advances in the structural characterization of complexes of therapeutic antibodies with PD-1 or PD-L1
by: Mengzhen Jiang, et al.
Published: (2023)

Mechanisms of Xiaozheng decoction for anti-bladder cancer effects via affecting the GSK3β/β-catenin signaling pathways: a network pharmacology-directed experimental investigation
by: Jingming Zhuang, et al.
Published: (2023)

Spontaneous rupture of unscarred uterus secondary to placental percreta in the third trimester of pregnancy after IVF and embryo transfer: a case report
by: Yanzhen Zhou, et al.
Published: (2021)

Gut microbiota-driven metabolic alterations reveal the distinct pathogenicity of chemotherapy-induced cachexia in gastric cancer
by: Jian Wu, et al.
Published: (2024)

Chinese herbal medicine, Jianpi Ligan decoction, improves prognosis of unresectable hepatocellular carcinoma after transarterial chemoembolization: a retrospective study
by: Tang CW, et al.
Published: (2016)

PD-1 Alleviates Cisplatin-Induced Muscle Atrophy by Regulating Inflammation and Oxidative Stress
by: Xiaoguang Liu, et al.
Published: (2022)

Tongbi Huoluo Decoction alleviates cartilage degeneration in knee osteoarthritis by inhibiting degradation of extracellular matrix
by: Weijian Chen, et al.
Published: (2023)

Exosome Mediated Delivery of miR-124 Promotes Neurogenesis after Ischemia
by: Jialei Yang, et al.
Published: (2017)

Yiqi Huayu decoction alleviates bleomycin-induced pulmonary fibrosis in rats by inhibiting senescence
by: Biao Zuo, et al.
Published: (2022)

Effect of radiotherapy on T cell and PD-1 / PD-L1 blocking therapy in tumor microenvironment
by: Chen Chen, et al.
Published: (2021)

Buyang Huanwu Decoction alleviates cerebral ischemic injury through modulating caveolin-1-mediated mitochondrial quality control
by: Yaqian Xu, et al.
Published: (2023)

Mesenchymal Stem Cell-Derived Exosomes Modulate Chondrocyte Glutamine Metabolism to Alleviate Osteoarthritis Progression
by: Kai Jiang, et al.
Published: (2021)

PD-1/PD-L1 Checkpoint Inhibitors in Tumor Immunotherapy
by: Jinhua Liu, et al.
Published: (2021)

Shugan Hewei Decoction Alleviates Cecum Mucosal Injury and Improves Depressive- and Anxiety-Like Behaviors in Chronic Stress Model Rats by Regulating Cecal Microbiota and Inhibiting NLRP3 Inflammasome
by: Yingying Yue, et al.
Published: (2021)

Wenshen Jianpi recipe, a blended traditional Chinese medicine, ameliorates proteinuria and renal injury in a rat model of diabetic nephropathy
by: Xiaodan Cao, et al.
Published: (2019)

Human adipose mesenchymal stem cell-derived exosomes alleviate fibrosis by restraining ferroptosis in keloids
by: Yuan Tian, et al.
Published: (2024)

Exosomes derived from HUVECs alleviate ischemia-reperfusion induced inflammation in neural cells by upregulating KLF14 expression
by: Jianxin Qin, et al.
Published: (2024)

Yiqi Jiedu Huayu Decoction Alleviates Renal Injury in Rats With Diabetic Nephropathy by Promoting Autophagy
by: Chen Xuan, et al.
Published: (2021)

Baitouweng decoction alleviates ulcerative colitis by regulating tryptophan metabolism through DOPA decarboxylase promotion
by: Junzhi Zhang, et al.
Published: (2024)

The potential effect and mechanism of Saikosaponin A against gastric cancer
by: Chao Wang, et al.
Published: (2023)

The Prognostic Value of Gastric Immune Prognostic Index in Gastric Cancer Patients Treated With PD-1/PD-L1 Inhibitors
by: Li Chen, et al.
Published: (2022)

Exosomal miR-132-3p from mesenchymal stem cells alleviated LPS-induced acute lung injury by repressing TRAF6
by: Jian-Hua Liu, et al.
Published: (2021)

Gegen-Qinlian decoction alleviates anxiety-like behaviors in methamphetamine-withdrawn mice by regulating Akkermansia and metabolism in the colon
by: Xue Lu, et al.
Published: (2023)

Outcome of nonsurgical management of large cyst-like periapical lesions using a modified apical negative pressure irrigation system: a case series study
by: Danhua Ling, et al.
Published: (2024)

Qu-Zhuo-Tong-Bi Decoction Alleviates Gouty Arthritis by Regulating Butyrate-Producing Bacteria in Mice
by: Xianghui Wen, et al.
Published: (2021)